Development of Oxymetholone was done in the 60s by Syntex Pharmaceuticals. The company uses Anadrol as the commercial name for the compound.
1960- 1992: Anadrol was introduced in the market with the aim of treatment of anemia and osteoporosis. It was approved for human consumption by the Food and Drug Administration.
1993 – 1997: Syntex stopped the due to disinterest in finances, and its use in some foreign countries was halted.
1998: Studies discovered that the drug has a lot of potential despite its unavailability in a lot of countries. Its compound was f to efficient and safe for use against the HIV syndrome. This is the study that quickly brought the drug to the market.
It mainly competes with Dianabol, another compound known to have almost similar effects. During the 60s regulation of the drug was not seriously done. Hence the drug was also given to children. Commonly called A-bombs or A50, the drug was developed to help in muscle growth for patients who were suffering from anemia. The compound gained a lot of popularity in the bodybuilding industry due to the promotion by Dan Duchaine.
Anadrol was classified as a Schedule III drug by the FDA. It is classified because bodybuilders and athletes who use them can develop a physical and psychological dependence.
What is Anadrol?
Classified in the Dihydrotesterone steroid group, Anadrol has far different body effects than other drugs in the group. The main change, made to Anadrol is the addition of a group called 2- hydroxy methylene into its chemical structure. 2-hydroxy methylene made it among the most hardcore steroids consumed orally on the planet. Besides being consumed orally, the drug is also developed in liquid form and can be administered by injection.
Prescription of the drug was done for anemic patients to increase hemoglobin levels and red blood cell count in the body. The drug can enhance erythropoiesis, protein synthesis, at rates that are very high hence the use for this purpose. It is this reason that has made the drug also get into the body building industry. It can be used in muscle building since it is moderately androgenic and highly anabolic.
Athletes use Anadrol during bulking cycles to obtain its enormous gains. It boosts their endurance and stamina while retaining muscular nitrogen which promotes better, longer workouts with less soreness and fatigue.
Medical Uses and Composition of Anadrol
The compound was primarily developed for the treatment of anemia and osteoporosis and stimulation of muscle growth in weak or malnourished patients. It is also active in the promotion of extensive gains in the body mass through improvement of protein synthesis hence it is used by athletes and bodybuilders.
Oxymetholone has a high ratio of androgenic to anabolic activity. Since it is a DHT derivative, it isn’t substrate for aromatase, and it cannot be aromatized to form estrogenic metabolites. It is associated with quite a high estrogenicity which can cause gynecomastia or water retention.
Dihydrotestosterone (DHT) is the main compound from which Anadrol is derived. There are other components including Masteron, Promobolan, Winstrol, Anavar and others that are also derivatives of parent anabolic steroid DHT. The difference of Anadrol from DHT is the addition of a group that is attached and a 2-hydro methylene compound also attached to carbon in its first ring in the steroid structure.
It this modification that makes Anadrol remain active while in muscle tissues, where the DHT compound would normally be made inactive through reduction of other metabolites. 3-hydroxysteroid dehydrogenase is the enzyme that is responsible for rendering the DHT compound inactive. It does not interact with Anadrol hence allows it to be highly active in the muscle tissue leading to very high potency. With an anabolic rating of 320, three times stronger than the testosterone rating, Anadrol can oppress the production of the latter’s hormone in the body.
Most of the Anadrol prescriptions are given in oral form. The dosage for man is usually 50 to 100 milligrams per day, and it’s taken with other steroid associated with wet bulking. Women are prescribed 10 milligrams per day, but it should be taken mainly by women doing fitness or bodybuilding.
There is also dosage for different levels of users who take or are starting to take the drug. For beginners using it for athletic or bodybuilding purposes, a dosage of 25 to 50 milligrams per day is advised. Intermediate athletes and bodybuilders, a range of 50 to 100 milligrams per day are recommended. Advanced, users who have taken the drug for some time, can take as much as 150 milligrams per day.
A 50 milligram limit per day is however recommended due to the drug’s high potency and strength. Anadrol capsules should be considered over injectables due to their low bioavailability. It should also not be taken with other different oral steroids and not for more than eight weeks.
Warnings and Recommendations about Anadrol
Below are some of the recommended instructions and warnings concerning the use of Anadrol
- Before the use of Anadrol, one should remember that use of this substance it for persons 18 years
old or above.
- Use of the drug by minors can lead to stunted development of their bodies.
- Use of Anadrol requires following a work out religiously or else it will result in one getting big without any real muscle development. Muscles will degenerate quickly and you will have wasted your money and time. You should work out at least three times a week when combining Anadrol and bodybuilding.
- Avoid use of the anabolic steroid for an extended period. This increases the chances if being affected by side effects. A caution should be taken since this drug affects normal body processes just like other medicines. Some of the effects include reduced production of testosterone in the body.
Dose chart for Anadrol
A chart is provided to for those interested in Anadrol usage. The user should choose the ideal cycle length and perfect treatment before purchasing the drug.
• The beginner level requires on to take 25 to 50 milligrams for a period of 6 to 10 weeks.
• The intermediate level requires one to take 50 mg to 75 milligrams for six weeks
• The advanced level requires one to take 100 to 120 milligrams for four weeks.
The advanced user should not ignore the effects of the stack during the dosage as stacks increase efficacy associated with steroids. Although they increase efficacy, they also worsen the side effects potentially associated with Anadrol.
Anadrol Usage by Women
There are different opinions from various analysts and health experts on the effect of using Anadrol on women. Some claim that it is fit for consumption while others differ. Although it has a low androgenic rating, it presents a significant androgenic- related side effects that sometimes result in virilization. Virilization relates to the development of masculine features in women. Women should use steroids with far less androgenic properties.
Some of these characteristics are:
- Excess body hair growth
- Enlargement of the clitoris
- Hair loss that leads to baldness
- Deepening of the voice
Side Effects Related to Anadrol
Anadrol has both mild and severe side effects. Most of the side effects are associated with the improper administration of the drug. Some of the mild effects associated with it are insomnia, excitation, and anxiety. Diarrhea, headaches, abnormal skin sensations, nausea, change in sexual desire and acne can also be experienced.
Below are some of the severe side effects associated with Anadrol
- Water retention: It causes some amount of bloating in the body. The user should check that the maintenance of a healthy blood pressure. To counter these anti-estrogen medications are recommended plus some diuretics can also help.
- Accelerated hair loss and acne: Male pattern baldness and severe acne are discovered in some people. Men already exhibiting these conditions are always at greater risks hence they should consider it before taking this drug.
- Gynecomastia: This side effect comes because Anadrol is highly estrogenic. Users should supplement it with anti- estrogen medication to help control the estrogen levels in the body and prevent this related side effect.
- Suppression of testosterone: The chemicals in Anadrol bind with proteins associated with testosterone. This can lead to reduced production of the testosterone hormone naturally. Users should use maintenance doses for testosterone to avoid reduced production. Low testosterone has some symptoms that the user should look out for, like depression, fatigue, erectile dysfunction and low libido.
- Hepatotoxicity: Anadrol has chemical components that intoxicate the liver. To avoid this risk, one should take minimal dosage as possible for the shortest time to achieve the best results. The drug should be consumed in the recommended period to reduce the risk of damage to the liver. Consumption of alcohol and paracetamol or acetaminophen should be avoided at all costs. Anadrol also has an adverse impact on the cardiovascular system in an extreme manner. It causes the production of large alterations in the blood cholesterol profiles. Women can also experience a slight change in their menstrual periods and clitoral enlargement.
Besides use improper use, there are side effects related to withdrawal from use of Anadrol. Use of the drug creates some dependence. Hence withdrawal symptoms will be felt once you stop using the drug.
Edema, prostatic enlargement, hepatic abnormalities, urinary obstruction and decreased ejaculation, can also be experienced. Other effects include chest pain, mental problems, unusual bleeding weight gain and difficulty in breathing will be experienced.
Stacking Related to Anadrol
Stack options have limited impact on the liver compared to other steroid compounds. It should not be used with other oral steroids since the have little synergistic effects that counterbalance liver damage risks. There are other drugs like Andriol and Trenbolone that stack well Anadrol since they are not processed in the liver. A dose of 50 milligrams of Trenbolone or 240 milligrams of Andriol plus 50 milligrams of Anadrol per day is recommended to improve the synergistic effects.
Post cycle therapy should be considered when creating one’s Anadrol stack. Testosterone and anti-estrogen supplement should be taken for two weeks after you have stopped the Anadrol dosage. This will reduce and prevent estrogen build up and low testosterone in the body which prevents the occurrence of side effects.
The cycles that include Anadrol are usually intended for strength-gaining, bulking and overall gain of mass. They should not be used for cutting, pre-contest or fat loss. Limiting of cycle length and dosage of Anadrol is recommended due to its hepatotoxic nature. Some rules should be followed for the use of Anadrol.
- A dose of 100 milligrams per day should be employed for those using injectable or oral Anadrol. Any amounts above this dosage increase the risks of side effects. Hence this dose should be followed strictly.
- High consumption of an Anadrol dosage should be done with a short cycle length. A 100 milligrams dose per day should be administered for four weeks. A 25-milligram dose per day should be used for eight weeks.
- The user should take breaks in between cycles and the number of cycles done per year should be limited to protect the liver from damage. Consumption for Anadrol should not be more than 16 to 18 weeks for one year. You should have two 8-week cycles, three6 – week period or four 4 – week cycles depending on the one’s dosage and preference.
- Anadrol Post cycle therapy should follow the Anadrol cycle. It should have a dosage of Nolvadex and Clomid for a period of 4 to 6 weeks. To counter the side effects such as testicular atrophy HCG should be included in the Post Cycle Therapy.
Anadrol Post Cycle Therapy
A well planned and extensive post-cycle therapy is recommended since Anadrol is a very potent steroid. This treatment ensures the gains acquired during the use of the steroids are kept.it also helps users avoid most of the side effects related to suppressed production of testosterone. Post –cycle therapy should be started three days after taking the last dose of the steroid owing to Anadrol’s extremely short half-life and its short-ester ness.
If Anadrol can be used in combination with another long-estered steroid, post-cycle therapy should be started 14 to 18 days after the last dose. Nolvadex and Clomid can help kick-start natural production of testosterone in the body.
Below are the time frames that are related to post-cycle therapy.
- For a period of 1 to 2 weeks, the user should take 150 mg of Clomid and 40mg of Nolvadex per day.
- For a period of 3 to 4 weeks, the user should take 100 mg of Clomid and 20mg of Nolvadex per day.
- For five weeks, the user should take 50mg of Clomid and 10mg of Nolvadex per day.
Results Associated with use of Anadrol
The drug provides different results depending on once dosage, diet, stacks and exercise routine. These are the most important factors that help in achieving the best results from Anadrol.
Users of this steroid report a gain of 10 to 15 pounds in six weeks. This varies with different people as some individuals gain 30 pounds within the six week period if they have the right diet, exercise, stacks and use of relatively large doses. Others may experience fewer benefits if they have a low consumption of protein and calories, a small dosage and irregular workout routine.
For athletes, Anadrol helps them gain significant stamina and strength. It gives male athletes better performance since it allows longer, harder and faster runs which are vital factors for performance. Fitness enthusiasts have better workout routines since it helps burn body fat and increases mass. This is achievable due to the increased energy and reduced fatigue after the workout.
Legal Issues Related to Anadrol
In the 1980s the FDA made Anadrol a controlled substance due to its potential for abuse. It was limited to use by doctors for treatment of autoimmune and anemic disorders. Acquisition of the drug is restricted to those with prescriptions only. Use or possession of the drug besides the prescription is at the user’s own risk. This makes access to the drug hard unless one uses online platforms. The user can buy the drug using an internet source then it is shipped into the country.
Frequently Asked Questions
1. What amount of Anadrol should be taken?
Anadrol is mainly administered in oral form. According to the dosage, one should take 50 mg less than fellow athletes. For beginners, a 25mg daily dosage should assist in deciding once tolerance. The next cycle allows for one to increase the dosage to 50 milligrams taking into consideration the side effects which is one of the best ways of determining the best way to take the drug. It will help the user reduce the risk of getting side effects associated with the drug.
This compound is quite common, and its production is a guarantee. Purchase of the steroid can be made as an underground grade or pharmaceutical grade. There is a difference between the quality and the price of Anadrol. High quality Anadrol can be acquired at relatively higher prices than low-quality compounds. It is also reasonably priced and affordable compared to other more exotic and rare anabolic steroid compounds.
For those with a prescription from a certified physician, you can find and buy the drug at any pharmacy. Those without prescriptions cannot access the drug legally. Purchase of Anadrol will be at one’s own risk. One should avoid the acquisition of the compounds from street vendors, instead look for reliable and well-known merchants online or buy legal alternative to it. Pharmaceutical grade Anadrol goes for a price range of between 1.30 to 2.50 dollars per 50 mg tablet. Underground quality grade Anadrol goes for around 0.75 to 2.30 dollar per tablet. The price can also vary depending on the source and dealers.
3. What are some of the results I should expect after use?
For men, a gain of 10 to 15 pounds should be regularly observed within a six-week cycle with a dose of 50 mg daily. The benefits also depend on the amount of dose taken by the user, taking a large dose will lead to better gains. Results also relate directly to exercise and diet consumed by the user. You should make sure to have a proper diet and regular exercises for better results. Steps should be taken to make the best out of the drug taking cycle to maximize the results.
4. Which is better? Anadrol or Dianabol?
Both steroids are orally taken and provide substantial gains within a relatively short period. Both offer gains of 20 to 30 pounds for six weeks compounded with the right exercise and diet program.
Below are some of the pros and cons of both Anadrol and Dianabol,
It offers great results with higher doses within an eight-week cycle. Anadrol does not aromatize meaning less abundance of estrogen in the body during a cycle
It provides relatively large gains but not compared to Anadrol over the same usage period. It provides a sense of well-being instead of depression and fatigue and doesn’t cause water retention
Gains acquired using Anadrol often come with significant side effects such as high blood pressure, massive bloating, headaches and general malaise.
Benefits obtained after the cycle do not last for long.
One can use both compounds in moderate doses with short cycles complemented with a supplement to protect the liver. A treatment involving a 10-week period taking 100mg of Anadrol and 50 mg of Dianabol daily. The use of both will help counter act the side effects related to both the drugs.
5. Are Anadrol Test cycles safe?
Anadrol test cycle is recommended besides being safe. Consumption of Anadrol for sale stops the body from producing natural testosterone. The addition of testosterone during the cycle is important in preventing the symptoms associated with low testosterone. A dedicated Post-cycle therapy and precautions should be taken into consideration while undertaking the cycle. For short gains within a short period, with reduces side effects one should use Anadrol.
6. Which is the best option between injections, liquid or tablet Anadrol?
Liquids and tablets of Anadrol offer low bioavailability compared to the injected dose. To get the most out of the drug users should use the injectable form.
The use of Anadrol should be done within the recommended limits. Users should also make sure they adhere to a proper exercise schedule and a healthy diet. This will reduce the harmful side effects associated with the drug hence promoting the purpose for its development. Governments should not limit the use of the compound, as long as there are clear guidelines on it administration. Well established regulations will reduce the rate of dependence on the drug and also limit those who have access and who sell Anadrol. The user should also take regular advice from doctors to reduce some of the side effects related to the use of the compound.